How it works
The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering. Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.
Generics
Rosuvastatin
used for
Cholesterol Control
Indication
Rosuvastatin is indicated for the treatment of: Hyperlipidemia and Mixed Dyslipidemia As adjunctive therapy to diet to reduce elevated Total-C, LDL-C, ApoB, nonHDL-C, and triglycerides and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia.
Side Effects
Headache, dizziness, constipation, nausea, abdominal pain, myalgia, asthenia, diabetic mellitus Pruritus, rash and urticaria , Hypersensitivity reactions including angioedema, myopathy, rhabdomyolysis, pancreatitis.
Dosage
Adults : The dose range for (Rosuvastatin) is 5mg to 40mg orally once daily. The usual starting dose is 10-20mg. Max : 40mg once daily , but only in severe hypercholesterolaemia where 20mg is inadequate. Elderly : Over 70 yr , initially 5mg once daily. Children : Under 10 yr , Not recommended or as directed by your physician.
Storage 
Store this medicine at room temperature, away from direct light and heat.
Precautions
When initiating (Rosuvastatin) therapy or switching from another HMG-CoA reductase inhibitor therapy, the appropriate (Rosuvastatin) starting dose should first be utiized, and only then titrated according to the patient's response and individualized goal of therapy.