Bosentan monohydrate is a medication used to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the arteries of the lungs. It is a selective endothelin receptor antagonist that works by blocking the action of endothelin, a substance in the body that narrows blood vessels and increases blood pressure.
Bosentan monohydrate is available as an oral tablet and is typically taken twice a day. The dose will vary depending on the individual's age, weight, and overall health.
Common side effects of bosentan monohydrate include headache, flushing, nausea, diarrhea, stomach pain, and abnormal liver function tests. Serious side effects may include liver damage, anemia, low blood pressure, and birth defects if taken during pregnancy.
Bosentan monohydrate should not be taken by pregnant women or women planning to become pregnant. It can harm an unborn baby and is classified as a pregnancy Category X medication. Close monitoring of liver function is also recommended during treatment with bosentan monohydrate.