Glusimet 50/500mg Tablets is a combination medication used to treat type 2 diabetes. It contains two active ingredients, Metformin hydrochloride and Glimepiride, which work together to help lower blood sugar levels. Metformin hydrochloride helps to decrease the amount of glucose produced by the liver, while Glimepiride helps to increase the insulin production in the body. Glusimet 50/500mg Tablets are usually taken once or twice daily with food, as directed by a doctor. It is important to follow a proper diet and exercise program while taking this medication to help control blood sugar levels.