Losartan potassium and hydrochlorothiazide is a combination medication used to treat high blood pressure, also known as hypertension. It contains two active ingredients: losartan potassium, which is an angiotensin II receptor blocker (ARB), and hydrochlorothiazide, which is a diuretic (water pill).
Losartan potassium works by blocking the action of a hormone called angiotensin II, which narrows blood vessels and increases blood pressure. Hydrochlorothiazide works by increasing urine output, which helps to reduce excess fluid in the body and lower blood pressure.
Losartan potassium and hydrochlorothiazide comes in tablet form and is typically taken once daily, with or without food. The dosage and duration of treatment will depend on the individual patient's blood pressure and response to treatment. It is important to take the medication exactly as prescribed and to avoid missing doses.
Common side effects of losartan potassium and hydrochlorothiazide include dizziness, headache, fatigue, dry cough, and stomach upset. More serious side effects are rare, but can include low blood pressure, electrolyte imbalances, and kidney problems. People with a history of liver or kidney disease, electrolyte imbalances, or who are taking other medications that may interact with losartan potassium and hydrochlorothiazide should use the medication with caution or avoid it altogether.
It is important to speak with a healthcare provider before starting losartan potassium and hydrochlorothiazide, especially if there is a history of liver or kidney disease, electrolyte imbalances, or if taking other medications that may interact with it. The medication can also interact with alcohol and grapefruit juice, so it is important to avoid consuming these while taking this medication.