Zestoretic 20/12.5mg tablets are a prescription medication that contains two active ingredients: lisinopril and hydrochlorothiazide. Lisinopril is an ACE (angiotensin-converting enzyme) inhibitor, while hydrochlorothiazide is a diuretic.
This combination medication is used to treat hypertension (high blood pressure) in adults. By lowering blood pressure, Zestoretic helps reduce the risk of heart attacks, strokes, and other cardiovascular diseases.
The lisinopril in Zestoretic works by blocking the action of ACE, an enzyme that constricts blood vessels and raises blood pressure. This allows blood vessels to relax and widen, reducing the pressure on the walls of the arteries.
Hydrochlorothiazide works by increasing the amount of salt and water that the kidneys remove from the bloodstream. This helps to reduce the volume of blood in the body, which in turn reduces the pressure on the blood vessel walls.
Zestoretic 20/12.5mg tablets are taken orally, usually once a day, with or without food. The dosage and duration of treatment will depend on the individual's medical condition and response to treatment. It is important to take the medication exactly as prescribed by a healthcare professional.
Common side effects of Zestoretic may include dizziness, headache, cough, nausea, and fatigue. In rare cases, it may cause more serious side effects such as allergic reactions, electrolyte imbalances, kidney problems, or low blood pressure. It is important to seek medical attention if you experience any severe or persistent side effects.